The final defeat of Natchez survivors who had crossed the Mississippi marked the end of the Natchez as a people. French and Choctaw forces tracked down the refugees. 427 Natchez survivors were captured and shipped to Saint-Domingue (Haiti) to be sold as slaves. A small number escaped to live among the Chickasaw. The destruction of the Natchez was one of the most complete eliminations of a Native nation in colonial history.
European colonization of North America accelerated after 1600, with England, France, Spain, and the Netherlands establishing competing settlements along the Atlantic coast, the St. Lawrence River, the Gulf of Mexico, and the Mississippi Valley. The first permanent English settlement at Jamestown, Virginia (1607) struggled with starvation and conflict; the Plymouth colony (1620) and the Massachusetts Bay Colony (1630) followed. By the mid-1700s, thirteen English colonies stretched along the Atlantic seaboard, governed through a mix of royal charters, proprietary grants, and elected assemblies. The colonial economy depended on tobacco in Virginia and Maryland, rice and indigo in the Carolinas, and maritime trade in New England — all increasingly reliant on enslaved African labor after 1619. Conflict with Indigenous peoples over land was continuous, punctuated by major wars including King Philip's War (1675–1676) in New England and the Yamasee War (1715–1717) in the South. The French and Indian War (1754–1763), part of the global Seven Years' War, ended French power in North America and left Britain deeply in debt — triggering the taxation disputes that would lead to revolution.
427 Natchez enslaved; most of remainder killed or dispersed
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