Fort Union at the Missouri-Yellowstone confluence was the hub of the upper Missouri fur trade. Sitting Bull's attacks on Fort Union in 1864 announced his comprehensive rejection of the American economic and military presence in Hunkpapa territory. These raids differed from traditional warfare in their explicitly anti-American motivation — Sitting Bull was not raiding for horses or territory but to expel Americans from Sioux land entirely.
The Indian Wars encompass more than three centuries of armed conflict between the United States government, American settlers, and Indigenous nations — from the Powhatan Wars of the 1620s through the final Plains campaigns of the late 19th century. The eastern conflicts — King Philip's War (1675–1676), the Tuscarora War (1711–1715), and the Creek and Seminole Wars — largely ended organized Indigenous resistance east of the Mississippi by the 1840s. On the Great Plains, the Sioux Wars (1854–1890), Red River War (1874–1875), and Nez Perce War (1877) followed the displacement wrought by the transcontinental railroad and the near-extinction of the American bison — an estimated 30 to 60 million animals reduced to fewer than 1,000 by 1890. The Ghost Dance religious movement and the massacre at Wounded Knee (December 29, 1890), in which US cavalry killed approximately 250 Lakota men, women, and children, marked the effective end of armed resistance. The Dawes Act (1887) allotted reservation land to individual families, opening millions of acres to white settlement and reducing Indigenous landholdings by about two-thirds over the following decades.
Light casualties; Fort Union eventually abandoned in 1867
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